Nature Lipidomics Gateway homepage

Experimental data

Lipidomics studies on human plasma

NIDDK / NIST human plasma sample analysis

Lipidomics studies on macrophages

RAW 264.7 cells
- Kdo₂-Lipid A time course experiments
- Compactin/Kdo₂-Lipid A time course experiments

Primary macrophages
- Thioglycolate-elicited peritoneal macrophages (TGEM)
  - Compactin/Kdo₂-Lipid A time course experiments
  - Foam cell study with wild-type and LDLR(-/-) mice
- Bone marrow-derived macrophages (BMDM)
- Compare results from TGEM and BMDM treated with Kdo₂-Lipid A (3 time points: 0,6,24 hrs)
Compare results from RAW, TGEM, and BMDM for sterols treated with Kdo₂-Lipid A (full time course: 8 time points)

Microarray analysis of macrophages

RAW 264.7 cells
- Kdo₂-Lipid A time course experiments
- Compactin/Kdo₂-Lipid A time course experiments (2 time points: 12, 24hrs)
- Compactin/Kdo₂-Lipid A time course experiments (full time course: 7 time points)

Primary macrophages
- Thioglycolate-elicited macrophages
- Bone marrow-derived macrophages

Subcellular fractionation studies on macrophages

Measurements of lipid quanitities present in various cell fractions (cytoplasm, ER, mitochondria, nucleus, plasma membrane) for control and treatment with
Kdo₂-Lipid A

RAW 264.7 cells
- Kdo₂-Lipid A experiments