Lipidomics update - July 2009
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Prostaglandin E2
Injury, infection and autoimmune disease can produce red and painful swelling, mediated by bioactive eicosanoids including prostaglandin E2. PGE2 signaling is also implicated in maintenance of homeostasis, and in the diverse disease processes that arise when that maintenance slips.
Research highlights
Fat finding in disease: Lipids coming 'omeNew lipidomics techniques define specific lipid profiles produced during disease states or found on invading pathogens, opening new avenues for treatment.
Low-fat marrow: Good for the bloodBone-marrow adipocytes reduce hematopoiesis and may represent a novel target for enhancing post-transplant recovery.
Cancer and Prostaglandin E2: Don't make it, or break it?A lack of prostaglandin dehydrogenase prevents catabolism of prostaglandin E2, helping cancer cells both to evade the immune system and circumvent drug treatment.
Reducing cardiovascular risk: Even less is moreLowering LDL cholesterol and blood pressure beyond current guidelines reduces atherosclerotic progression.
News
- Drug quells anxiety in early trials
- Mouse patent sparks 'uncivil' spat
- Californian universities caught in budget hell
- Italy outsources peer review to NIH
- Research parks feel the economic pinch
Events calendar
6th GERLI Lipidomics meeting, Bioactive Lipids, Nutrition and Health
1 - 3 July 2009
21 - 24 November, 2010
Research library
- Mitochondrial long chain fatty acid beta-oxidation in man and mouse. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Localisation of DivIVA by targeting to negatively curved membranes. The EMBO Journal
- more from the research library
