Lipidomics update - September 2010
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Cyclic phosphatidic acid (cPA)
An analogue of lysophosphatidic acid, with diametric effects, cPA is an anti-metastatic signaling lipid that negatively regulates PPARγ.
Research highlights
PPARγ regulators: Cyclic phosphatidic acid acts downCyclic phosphatidic acid is a second messenger and a competitive antagonist of PPARγ.
Localizing lipids: Subcellular distributionLipidomic study analyzes the subcellular localization of major membrane lipids in resting and activated macrophages.
Atherogenic signaling: Double troubleSynergistic activation of macrophages by mmLDL and LPS induces the expression of proinflammatory chemokines important in atherosclerosis.
Inflammation: The fat controllerNew anti-inflammatory adipokine controls metabolic function.
News
- Nano-hairpin peeks into cells
- Food firms test fry Pioneer's trans fat–free soybean oil
- Million-dollar problem cracked?
- US court suspends research on human embryonic stem cells
- Retraction recommended for enzyme-chip paper
Events calendar
Plant Lipids: Structure, Metabolism & Function
30 January - 4 February, 2011
8 - 13 May, 2011
Research library
- A Vibrio effector protein is an inositol phosphatase and disrupts host cell membrane integrity Science
- Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies Journal of Biological Chemistry
- more from the research library
