Research library - browse by date

This library is a growing collection of the most significant research advances and key review articles, categorized by subject areas, from across the literature.

  • August 2011

    • An "Exacerbate-reverse" Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease

      Munkacsi A., Chen F., Brinkman M., Higaki K., Gutiérrez G. et al.

      Journal of Biological Chemistry 286, (2011)

      [doi: 10.1074/jbc.M111.227645]

    • Kinetic analysis of Autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.

      Saunders L., Cao W., Chang W., Albright R., Braddock D. et al.

      Journal of Biological Chemistry (Published online 30 June 2011)

      [doi: 10.1074/jbc.M111.246884]

    • A Key Enzyme in the Biogenesis of Lysosomes Is a Protease That Regulates Cholesterol Metabolism

      Marschner K., Kollmann K., Schweizer M., Braulke T. and Pohl S.

      Science 33, (2011)

      [doi: 10.1126/science.1205677]

    • Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli

      Li C., Guan Z., Liu D. and Raetz C.

      Proceedings of the National Academy of Sciences (Published online 12 July 2011)

      [doi: 10.1073/pnas.1108840108]

    • Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

      Das S., Eder S., Schauer S., Diwoky C., Temmel H. et al.

      Science (Published online 8 July 2011)

      [doi: 10.1126/science.1198973]

    • The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction

      Perman J., Boström P., Lindbom M., Lidberg U., StÅhlman M. et al.

      Journal of Clinical Investigation 121, (2011)

      [doi: 10.1172/jci43068]

    • Lipid classification, structures and tools

      Fahy E., Cotter D., Sud M. and Subramaniam S.

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (Published online 1 June 2011)

      [doi: 10.1016/j.bbalip.2011.06.009] LIPID MAPS

    • Chiral lipidomics of E-series resolvins: Aspirin and the biosynthesis of novel mediators

      Oh S., Vickery T. and Serhan C.

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (Published online 1 June 2011)

      [doi: 10.1016/j.bbalip.2011.06.007]

    • Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis

      Xiao J., Engel J., Zhang J., Chen M., Manning G. et al.

      Proceedings of the National Academy of Sciences (Published online 19 July 2011)

      [doi: 10.1073/pnas.1109290108]

    • Phosphatidate phosphatase activity plays a key role in protection against fatty acid-induced toxicity in yeast

      Fakas S., Qiu Y., Dixon J., Han G., Ruggles K. et al.

      Journal of Biological Chemistry (Published online 27 June 2011)

      [doi: 10.1074/jbc.M111.258798]

    • Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels

      Ben-David O., Pewzner-Jung Y., Brenner O., Laviad E., Kogot-Levin A. et al.

      Journal of Biological Chemistry (Published online 24 June 2011)

      [doi: 10.1074/jbc.M111.261206]

    • Acid ceramidase expression modulates the sensitivity of A375 melanoma cells to dacarbazine

      Bedia C., Casas J., Andrieu-Abadie N., Fabrias G. and Levade T.

      Journal of Biological Chemistry (Published online 23 June 2011)

      [doi: 10.1074/jbc.M110.216382]

    • Phospholipid synthesis participates in the regulation of diacylglycerol required for membrane trafficking at the Golgi complex

      Sarri E., Sicart A., Lázaro-Diéguez F. and Egea G.

      Journal of Biological Chemistry (Published online 23 June 2011)

      [doi: 10.1074/jbc.M111.267534]

    • Novel functions of LBP-5 in Caenorhabditis elegans fat metabolism

      Xu M., Joo H. and Paik Y.

      Journal of Biological Chemistry (Published online 22 June 2011)

      [doi: 10.1074/jbc.M111.227165]

    • Structural basis of steroid hormone perception by the receptor kinase BRI1

      Hothorn M., Belkhadir Y., Dreux M., Dabi T., Noel J. et al.

      Nature 474, (2011)

      [doi: 10.1038/nature10153]

    • Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis

      Dambournet D., MacHicoane M., Chesneau L., Sachse M., Rocancourt M. et al.

      Nature Cell Biology (Published online 26 June 2011)

      [doi: 10.1038/ncb2279]

    • Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

      Dunn W., Broadhurst D., Begley P., Zelena E., Francis-McIntyre S. et al.

      Nature Protocols 6, (2011)

      [doi: 10.1038/nprot.2011.335]

    • Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways

      Yecies J., Zhang H., Menon S., Liu S., Yecies D. et al.

      Cell Metabolism 14, (2011)

      [doi: 10.1016/j.cmet.2011.06.002]

    • The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism

      Lee J., Giannikopoulos P., Duncan S., Wang J., Johansen C. et al.

      Nature Medicine 17, (2011)

      [doi: 10.1038/nm.2347]

    • Phospholipid-dependent regulation of the motor activity of myosin X

      Umeki N., Jung H., Sakai T., Sato O., Ikebe R. et al.

      Nature Structural and Molecular Biology 18, (2011)

      [doi: 10.1038/nsmb.2065]

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