Lipidomics update - August 2011
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Phytanic acid
This saturated fatty acid, which is abundant in animal fats, is metabolized by an unusual pathway.
Research highlights
Obesity and diabetes: Lipid boosts muscle and shrinks fatUrsolic acid, a pentacyclic triterpene found in apple peel, improves muscle mass and reduces fat by increasing the activation of the insulin and IGF1 receptors.
Cardiovascular disease: n-3 fatty acids reduce side effects of LXR agonistsBy acting on a key transcription factor for lipid biogenesis, in the opposite direction to the effect of LXR agonists, n-3 fatty acids may reduce a side effect of these potential drugs.
Cachexia: Putting the brakes on lipid lossLoss of adipose triglyceride lipase (and to some extent loss of hormone-sensitive lipase) can protect from tumour-associated loss of weight and white adipose tissue in mice.
News
- Cholesterol crawls
- Mice with human livers deal with drugs the human way
- Turbocharge your writing today
- Too many tasks
- Trial puts niacin—and cholesterol dogma—in the line of fire
Events calendar
Bioactive Lipids in Cancer, Inflammation and Related Diseases
18 - 21 September, 2011
Lipid metabolic diseases: novel developments in molecular pathology and therapy
2 - 4 October, 2011
Research library
- Chiral lipidomics of E-series resolvins: Aspirin and the biosynthesis of novel mediators Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis Proceedings of the National Academy of Sciences
- more from the research library
