Research library - Pharmacology
This library is a growing collection of the most significant research advances and key review articles, categorized by subject areas, from across the literature.
2012
Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression
Ying Z., Desikan R., Xu X., Maiseyeu A., Liu C. et al.
Journal of Lipid Research 53, (2012)
Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors
Gregus A., Doolen S., Dumlao D., Buczynski M., Takasusuki T. et al.
Proceedings of the National Academy of Sciences (Published online 9 April 2012)
Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice
Yu Z., Crichton I., Tang S., Hui Y., Ricciotti E. et al.
Proceedings of the National Academy of Sciences (Published online 9 April 2012)
Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease
Bozinovski S., Uddin M., Vlahos R., Thompson M., McQualter J. et al.
Proceedings of the National Academy of Sciences 109, (2012)
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
Panigrahy D., Edin M., Lee C., Huang S., Bielenberg D. et al.
The Journal of Clinical Investigation 122, (2012)
A catalytically silent FAAH-1 variant drives anandamide transport in neurons
Fu J., Bottegoni G., Sasso O., Bertorelli R., Rocchia W. et al.
Nat Neurosci 15, 64 - 69 (2012)
Primary amines protect against retinal degeneration in mouse models of retinopathies
Maeda A., Golczak M., Chen Y., Okano K., Kohno H. et al.
Nat Chem Biol (Published online 25 December 2011)
Lymphopenia induced by a novel selective S1P1 antagonist structurally unrelated to S1P
Fujii Y., Ohtake H., Ono N., Hara T., Sakurai T. et al.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1821, (2012)
Niacin and biosynthesis of PGD2 by platelet COX-1 in mice and humans
Song W., Stubbe J., Ricciotti E., Alamuddin N., Ibrahim S. et al.
The Journal of Clinical Investigation (Published online 2 April 2012)
Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis
Oyoshi M., He R., Kanaoka Y., Elkhal A., Kawamoto S. et al.
Proceedings of the National Academy of Sciences (Published online 27 March 2012)
Niacin: another look at an underutilized lipid-lowering medication
Creider J., Hegele R. and Joy T.
Nat Rev Endocrinol (Published online 21 February 2012)
An intrinsically labile [alpha]-helix abutting the BCL9-binding site of [beta]-catenin is required for its inhibition by carnosic acid
de la Roche M., Rutherford T., Gupta D., Veprintsev D., Saxty B. et al.
Nat Commun 3, 680 (2012)
Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice
Zhao J., Zhao J., Legge K. and Perlman S.
The Journal of Clinical Investigation 121, (2011)
Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases
Cao J., Zhou Y., Peng H., Huang X., Stahler S. et al.
Journal of Biological Chemistry 286, (2011)
ApoE-Directed Therapeutics Rapidly Clear [Beta]-Amyloid and Reverse Deficits in AD Mouse Models
Cramer P., Cirrito J., Wesson D., Lee C., Karlo J. et al.
Science (Published online 23 March 2012)
Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells
Soifer H., Souleimanian N., Wu S., Voskresenskiy A., Collak F. et al.
Journal of Biological Chemistry 287, (2012)
