Microarray data for Ebp: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Ebp
KLA  ATP  ATP+KLA
 phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), mRNA [NM_007898] KLA .77 .75 .66 .77 .61 .71 .67
 ATP .83 .83 1.15 .99 .88 .83 .95
 ATP+KLA .67 .72 .95 .79 .86 .75 .74

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ebp
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), mRNA [NM_007898] 25OHC/Ctl (?) 1.11 1.07 .99 1.05 .99 .90 .80
 25-OHC*/* (?) .93 1.20 .88 .88 .74 .68 .72
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ebp
KLA  Compactin  Compactin+KLA
 phenylalkylamine Ca2 antagonist (emopamil) binding protein (Ebp), mRNA [NM_007898] KLA 1.05 .97 .82 .70 .60 .63 .80
 Compactin 1.02 1.06 1.05 .98 1.07 1.05 1.06
 Compactin+KLA 1.02 .87 .92 .74 .60 .64 .89

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ebp
KLA  Compactin  Compactin+KLA
 phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), mRNA [NM_007898] KLA 1.18 1.17 1.04 .95 .71 .82 .91
 Compactin 1.24 1.16 1.12 1.16 1.15 1.03 1.06
 Compactin+KLA 1.14 .90 1.04 1.08 .76 .73 1.18