Microarray data for Hsd17b7: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Hsd17b7
KLA  ATP  ATP+KLA
 hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7), mRNA [NM_010476] KLA .87 .86 .78 .85 .86 .76 .77
 ATP 1.05 .94 1.22 .87 .69 .67 1.48
 ATP+KLA .88 .76 .91 .70 .53 .34 .36

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Hsd17b7
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7), mRNA [NM_010476] 25OHC/Ctl (?) 1.02 .96 .73 .49 .42 .38 .34
 25-OHC*/* (?) 1.07 .90 .78 .26 .12 .11 .13
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Hsd17b7
KLA  Compactin  Compactin+KLA
 hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7), mRNA [NM_010476] KLA 1.00 1.01 1.00 1.19 1.46 1.15 1.02
 Compactin 1.01 1.01 1.07 1.10 1.07 1.12 1.09
 Compactin+KLA .87 .98 1.08 1.31 1.86 1.30 1.19

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Hsd17b7
KLA  Compactin  Compactin+KLA
 hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7), mRNA [NM_010476] KLA 1.22 1.31 1.34 1.05 1.28 1.27 .85
 Compactin 1.09 1.09 1.05 1.12 1.13 1.08 1.15
 Compactin+KLA 1.16 1.28 1.63 1.19 1.25 1.12 1.00