Gene/Proteome Database (LMPD)

LMPD ID
LMP001011
Gene ID
14626
Species
Mus musculus (Mouse)
Gene Name
glycerol kinase 2
Gene Symbol
Gk2
Synonyms
GKTA; Gk-rs2
Alternate Names
glycerol kinase 2; GK 2; glycerokinase 2; glycerol kinase, testis specific 2; ATP:glycerol 3-phosphotransferase 2; glucokinase activity, related sequence 2
Chromosome
5
Map Location
5 E3|5 47.71 cM
EC Number
2.7.1.30

Proteins

glycerol kinase 2
Refseq ID NP_034424
Protein GI 6754000
UniProt ID Q9WU65
mRNA ID NM_010294
Length 554
RefSeq Status PROVISIONAL
MAASKQTSAGPLVGAVVQGTNSTRFLVFNSKTAELVCSHQVELTQEYPKEGWVEQDPKEILKSVYECIAKACEKLAEVNIDISNIKAIGVSNQRETTVVWDKFTGDPLYNAVVWLDLRTQSTVETLTKKIPGNSNFVKSKTGLPLSTYFSAVKLRWMLDNLRPIQKAVEEGRAMFGTIDSWLIWCMTGGVNGGIHCTDVTNACRTMLFNIHSLEWDKDLCDFFEIPMSILPNVCSSSEIYGLMTSGALEGVPISGCLGDQSAALVGQMCFHEGQAKNTYGTGCFLLCNTGQKCVFSEHGLLTTLAYKLGKNKPVFYALEGSVAIAGAVIRWLRDNFEIITTSGEVENLAREVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTNNRILMQLQADILHIPVVKSVMPETTALGAAMAAGAAEGVNVWSLEPEDLSTILMERYEPQIQATESEIRFSTWKRAVMKSMGWVTAKDPENGDNPVFSCLPLGFFIVSSMTLLIGARCVSTAEE

Gene Information

Entrez Gene ID
14626
Gene Name
glycerol kinase 2
Gene Symbol
Gk2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005741 IEA:UniProtKB-KW C mitochondrial outer membrane
GO:0005739 IDA:MGI C mitochondrion
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004370 IEA:UniProtKB-EC F glycerol kinase activity
GO:0019563 IEA:UniProtKB-UniPathway P glycerol catabolic process
GO:0006072 IEA:InterPro P glycerol-3-phosphate metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu00561 Glycerolipid metabolism
mmu03320 PPAR signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR018485 Carbohydrate kinase, FGGY, C-terminal
IPR018484 Carbohydrate kinase, FGGY, N-terminal
IPR018483 Carbohydrate kinase, FGGY, conserved site
IPR005999 Glycerol kinase

UniProt Annotations

Entry Information

Gene Name
glycerol kinase 2
Protein Entry
GLPK2_MOUSE
UniProt ID
Q9WU65
Species
Mouse

Comments

Comment Type Description
Catalytic Activity ATP + glycerol = ADP + sn-glycerol 3- phosphate.
Function Key enzyme in the regulation of glycerol uptake and metabolism.
Pathway Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
Similarity Belongs to the FGGY kinase family. {ECO:0000305}.
Subcellular Location Mitochondrion outer membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In sperm the majority of the enzyme is bound to mitochondria. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP001011 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6754000 RefSeq NP_034424 554 glycerol kinase 2

Identical Sequences to LMP001011 proteins

Reference Database Accession Length Protein Name
GI:6754000 GenBank AAD24551.1 554 glycerol kinase-like protein 2 [Mus musculus]
GI:6754000 GenBank AAH61147.1 554 Glycerol kinase 2 [Mus musculus]
GI:6754000 GenBank AAH50764.1 554 Glycerol kinase 2 [Mus musculus]
GI:6754000 GenBank EDL20343.1 554 glycerol kinase 2 [Mus musculus]
GI:6754000 SwissProt Q9WU65.1 554 RecName: Full=Glycerol kinase 2; Short=GK 2; Short=Glycerokinase 2; AltName: Full=ATP:glycerol 3-phosphotransferase 2; AltName: Full=Glycerol kinase, testis specific 2 [Mus musculus]

Related Sequences to LMP001011 proteins

Reference Database Accession Length Protein Name
GI:6754000 DBBJ BAC35939.1 535 unnamed protein product, partial [Mus musculus]
GI:6754000 GenBank AAH79449.1 554 Glycerol kinase 2 [Rattus norvegicus]
GI:6754000 GenBank EDL99625.1 554 glucokinase activity, related sequence 2 [Rattus norvegicus]
GI:6754000 RefSeq NP_001004077.1 554 glycerol kinase 2 [Rattus norvegicus]
GI:6754000 RefSeq XP_005068188.1 554 PREDICTED: glycerol kinase 2 [Mesocricetus auratus]
GI:6754000 RefSeq XP_006975425.1 554 PREDICTED: glycerol kinase 2 [Peromyscus maniculatus bairdii]