Gene/Proteome Database (LMPD)
LMPD ID
LMP005869
Gene ID
Species
Homo sapiens (Human)
Gene Name
nuclear receptor coactivator 1
Gene Symbol
Synonyms
F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74
Alternate Names
nuclear receptor coactivator 1; Hin-2 protein; PAX3/NCOA1 fusion protein; steroid receptor coactivator-1; renal carcinoma antigen NY-REN-52; class E basic helix-loop-helix protein 74
Chromosome
2
Map Location
2p23
EC Number
2.3.1.48
Summary
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Orthologs
Proteins
| nuclear receptor coactivator 1 isoform 1 | |
|---|---|
| Refseq ID | NP_003734 |
| Protein GI | 22538455 |
| UniProt ID | Q15788 |
| mRNA ID | NM_003743 |
| Length | 1441 |
| RefSeq Status | REVIEWED |
| MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQFAATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLANRNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE | |
| nuclear receptor coactivator 1 isoform 2 | |
|---|---|
| Refseq ID | NP_671756 |
| Protein GI | 22538457 |
| UniProt ID | Q15788 |
| mRNA ID | NM_147223 |
| Length | 1399 |
| RefSeq Status | REVIEWED |
| MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQFAATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLANRNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQDKKTEEFFSVVTTD | |
| nuclear receptor coactivator 1 isoform 3 | |
|---|---|
| Refseq ID | NP_671766 |
| Protein GI | 22538459 |
| UniProt ID | Q15788 |
| mRNA ID | NM_147233 |
| Length | 1440 |
| RefSeq Status | REVIEWED |
| MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQFAATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLANRNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005737 | IEA:Ensembl | C | cytoplasm |
| GO:0043005 | IEA:Ensembl | C | neuron projection |
| GO:0000790 | IDA:BHF-UCL | C | nuclear chromatin |
| GO:0005654 | TAS:Reactome | C | nucleoplasm |
| GO:0001012 | IEA:Ensembl | F | RNA polymerase II regulatory region DNA binding |
| GO:0001105 | NAS:BHF-UCL | F | RNA polymerase II transcription coactivator activity |
| GO:0050681 | NAS:UniProtKB | F | androgen receptor binding |
| GO:0003682 | IEA:Ensembl | F | chromatin binding |
| GO:0019899 | IPI:UniProtKB | F | enzyme binding |
| GO:0004402 | IEA:UniProtKB-EC | F | histone acetyltransferase activity |
| GO:0016922 | IPI:UniProtKB | F | ligand-dependent nuclear receptor binding |
| GO:0030374 | IDA:UniProtKB | F | ligand-dependent nuclear receptor transcription coactivator activity |
| GO:0035257 | IDA:UniProtKB | F | nuclear hormone receptor binding |
| GO:0047485 | IPI:UniProtKB | F | protein N-terminus binding |
| GO:0004871 | IEA:InterPro | F | signal transducer activity |
| GO:0003713 | IDA:UniProtKB | F | transcription coactivator activity |
| GO:0030521 | NAS:UniProtKB | P | androgen receptor signaling pathway |
| GO:0044255 | TAS:Reactome | P | cellular lipid metabolic process |
| GO:0032870 | IEA:Ensembl | P | cellular response to hormone stimulus |
| GO:0021549 | IEA:Ensembl | P | cerebellum development |
| GO:0021987 | IEA:Ensembl | P | cerebral cortex development |
| GO:0060206 | IEA:Ensembl | P | estrous cycle phase |
| GO:0021766 | IEA:Ensembl | P | hippocampus development |
| GO:0043967 | IEA:Ensembl | P | histone H4 acetylation |
| GO:0021854 | IEA:Ensembl | P | hypothalamus development |
| GO:0060713 | IEA:Ensembl | P | labyrinthine layer morphogenesis |
| GO:0007595 | IEA:Ensembl | P | lactation |
| GO:0008584 | IEA:Ensembl | P | male gonad development |
| GO:0060179 | IEA:Ensembl | P | male mating behavior |
| GO:0042698 | IEA:Ensembl | P | ovulation cycle |
| GO:0043065 | IEA:Ensembl | P | positive regulation of apoptotic process |
| GO:0045925 | IEA:Ensembl | P | positive regulation of female receptivity |
| GO:0045666 | IEA:Ensembl | P | positive regulation of neuron differentiation |
| GO:0045944 | IDA:UniProtKB | P | positive regulation of transcription from RNA polymerase II promoter |
| GO:0000435 | IDA:UniProtKB | P | positive regulation of transcription from RNA polymerase II promoter by galactose |
| GO:0045893 | IDA:UniProtKB | P | positive regulation of transcription, DNA-templated |
| GO:2001038 | IEA:Ensembl | P | regulation of cellular response to drug |
| GO:0032355 | IEA:Ensembl | P | response to estradiol |
| GO:0032570 | IEA:Ensembl | P | response to progesterone |
| GO:0032526 | IEA:Ensembl | P | response to retinoic acid |
| GO:0044281 | TAS:Reactome | P | small molecule metabolic process |
| GO:0006351 | IDA:UniProtKB | P | transcription, DNA-templated |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| hsa04919 | Thyroid hormone signaling pathway |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| REACT_147904 | Activation of gene expression by SREBF (SREBP) |
| REACT_200608 | Transcriptional activation of mitochondrial biogenesis |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR010011 | Domain of unknown function DUF1518 |
| IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| IPR017426 | Nuclear receptor coactivator |
| IPR028819 | Nuclear receptor coactivator 1 |
| IPR008955 | Nuclear receptor coactivator Src-1 |
| IPR014920 | Nuclear receptor coactivator, Ncoa-type, interlocking |
| IPR009110 | Nuclear receptor coactivator, interlocking |
| IPR000014 | PAS domain |
| IPR013767 | PAS_fold |
| IPR014935 | Steroid receptor coactivator |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=SRC-1A, SRC1a; IsoId=Q15788-1; Sequence=Displayed; Name=2; Synonyms=SRC-1E, SRC1e; IsoId=Q15788-2; Sequence=VSP_011739; Note=Major form. Contains a domain at its C-terminus (1241-1399) that is able to mediate transactivation.; Name=3; Synonyms=SRC-1 (-Q); IsoId=Q15788-3; Sequence=VSP_011738; |
| Catalytic Activity | Acetyl-CoA + [histone] = CoA + acetyl- [histone]. |
| Disease | Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children. |
| Domain | Contains 7 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs. LXXLL motifs 3, 4 and 5 are essential for the association with nuclear receptors. LXXLL motif 7, which is not present in isoform 2, increases the affinity for steroid receptors in vitro. |
| Domain | The C-terminal (1107-1441) part mediates the histone acetyltransferase (HAT) activity. |
| Function | Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3. {ECO |
| Interaction | P59598:Asxl1 (xeno); NbExp=2; IntAct=EBI-455189, EBI-5743705; P03372:ESR1; NbExp=10; IntAct=EBI-455189, EBI-78473; P19785:Esr1 (xeno); NbExp=2; IntAct=EBI-455189, EBI-346765; Q63ZY3:KANK2; NbExp=4; IntAct=EBI-455189, EBI-2556193; P25799:Nfkb1 (xeno); NbExp=2; IntAct=EBI-455189, EBI-643958; Q13133:NR1H3; NbExp=14; IntAct=EBI-455189, EBI-781356; P06536:Nr3c1 (xeno); NbExp=2; IntAct=EBI-455189, EBI-1187143; Q9BTK6:PAGR1; NbExp=4; IntAct=EBI-455189, EBI-2372223; P28065:PSMB9; NbExp=3; IntAct=EBI-455189, EBI-603300; P10276:RARA; NbExp=3; IntAct=EBI-455189, EBI-413374; P19793:RXRA; NbExp=5; IntAct=EBI-455189, EBI-78598; |
| Ptm | Sumoylated; sumoylation increases its interaction with PGR and prolongs its retention in the nucleus. It does not prevent its ubiquitination and does not exert a clear effect on the stability of the protein. |
| Ptm | Ubiquitinated; leading to proteasome-mediated degradation. Ubiquitination and sumoylation take place at different sites. |
| Sequence Caution | Sequence=AAA64187.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=AAC50305.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; |
| Similarity | Belongs to the SRC/p160 nuclear receptor coactivator family. |
| Similarity | Contains 1 PAS (PER-ARNT-SIM) domain. |
| Similarity | Contains 1 bHLH (basic helix-loop-helix) domain. |
| Subcellular Location | Nucleus {ECO |
| Subunit | Interacts with the methyltransferase CARM1 (By similarity). Interacts with NCOA6 and NCOA2. Interacts with the FDL motif of STAT5A and STAT5B. Interacts with the LXXLL motif of STAT6. Interacts with STAT3 following IL-6 stimulation. Interacts with the basal transcription factor GTF2B. Interacts with the histone acetyltransferases EP300 and CREBBP. Interacts with PCAF, COPS5, NR3C1 and TTLL5/STAMP. Interacts with PSMB9. Interacts with UBE2L3; they functionally interact to regulate progesterone receptor transcriptional activity. Interacts with PRMT2 and DDX5. Interacts with ASXL1. Interacts with PRMT6. Interacts (via LXXLL 1, 2 and 3 motifs) with RORC (via AF-2 motif). Interacts in a ligand-dependent fashion with RXRA. {ECO |
| Tissue Specificity | Widely expressed. |
| Web Resource | Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/ncoa1/"; |
Identical and Related Proteins
Unique RefSeq proteins for LMP005869 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 22538455 | RefSeq | NP_003734 | 1441 | nuclear receptor coactivator 1 isoform 1 |
| 22538457 | RefSeq | NP_671756 | 1399 | nuclear receptor coactivator 1 isoform 2 |
| 22538459 | RefSeq | NP_671766 | 1440 | nuclear receptor coactivator 1 isoform 3 |
Identical Sequences to LMP005869 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:22538457 | EMBL | CAA04372.1 | 1399 | steroid receptor coactivator 1e [Homo sapiens] |
| GI:22538459 | GenBank | AAC50631.1 | 1440 | steroid receptor coactivator-1 F-SRC-1 [Homo sapiens] |
| GI:22538457 | GenBank | AAI11535.1 | 1399 | Nuclear receptor coactivator 1 [Homo sapiens] |
| GI:22538457 | GenBank | EAX00747.1 | 1399 | nuclear receptor coactivator 1, isoform CRA_b [Homo sapiens] |
| GI:22538455 | GenBank | ABS29266.1 | 1441 | nuclear receptor coactivator 1 [Homo sapiens] |
| GI:22538455 | GenBank | ABW61205.1 | 1441 | Sequence 2 from patent US 7279325 |
| GI:22538459 | GenBank | AEC23628.1 | 1440 | Sequence 43 from patent US 7867500 |
| GI:22538455 | GenBank | AER79660.1 | 1441 | Sequence 3 from patent US 8048663 |
| GI:22538455 | GenBank | AHD77264.1 | 1441 | Sequence 22397 from patent US 8586006 |
| GI:22538457 | GenBank | AHD77265.1 | 1399 | Sequence 22398 from patent US 8586006 |
| GI:22538459 | GenBank | AHD77266.1 | 1440 | Sequence 22399 from patent US 8586006 |
| GI:22538455 | RefSeq | XP_005264682.1 | 1441 | PREDICTED: nuclear receptor coactivator 1 isoform X1 [Homo sapiens] |
| GI:22538459 | RefSeq | XP_005264683.1 | 1440 | PREDICTED: nuclear receptor coactivator 1 isoform X2 [Homo sapiens] |
| GI:22538457 | RefSeq | XP_005264684.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform X3 [Homo sapiens] |
| GI:22538457 | RefSeq | XP_005264685.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform X4 [Homo sapiens] |
| GI:22538455 | SwissProt | Q15788.3 | 1441 | RecName: Full=Nuclear receptor coactivator 1; Short=NCoA-1; AltName: Full=Class E basic helix-loop-helix protein 74; Short=bHLHe74; AltName: Full=Protein Hin-2; AltName: Full=RIP160; AltName: Full=Renal carcinoma antigen NY-REN-52; AltName: Full=Steroid receptor coactivator 1; Short=SRC-1 [Homo sapiens] |
Related Sequences to LMP005869 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:22538457 | DBBJ | BAF82708.1 | 1399 | unnamed protein product [Homo sapiens] |
| GI:22538459 | EMBL | CAA04371.1 | 1441 | steroid receptor coactivator [Homo sapiens] |
| GI:22538459 | GenBank | ABW61205.1 | 1441 | Sequence 2 from patent US 7279325 |
| GI:22538459 | GenBank | AER79660.1 | 1441 | Sequence 3 from patent US 8048663 |
| GI:22538455 | GenBank | JAA07840.1 | 1441 | nuclear receptor coactivator 1 [Pan troglodytes] |
| GI:22538455 | GenBank | JAA29053.1 | 1441 | nuclear receptor coactivator 1 [Pan troglodytes] |
| GI:22538457 | RefSeq | XP_003309007.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform X3 [Pan troglodytes] |
| GI:22538457 | RefSeq | XP_004028974.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform 1 [Gorilla gorilla gorilla] |
| GI:22538455 | RefSeq | XP_008950641.1 | 1441 | PREDICTED: nuclear receptor coactivator 1 isoform X1 [Pan paniscus] |
| GI:22538455 | RefSeq | XP_008950642.1 | 1441 | PREDICTED: nuclear receptor coactivator 1 isoform X1 [Pan paniscus] |
| GI:22538455 | RefSeq | XP_008950643.1 | 1441 | PREDICTED: nuclear receptor coactivator 1 isoform X1 [Pan paniscus] |
| GI:22538459 | RefSeq | XP_008950644.1 | 1440 | PREDICTED: nuclear receptor coactivator 1 isoform X2 [Pan paniscus] |
| GI:22538457 | RefSeq | XP_008950645.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform X3 [Pan paniscus] |
| GI:22538457 | RefSeq | XP_008950646.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform X3 [Pan paniscus] |
| GI:22538455 | RefSeq | XP_009440407.1 | 1441 | PREDICTED: nuclear receptor coactivator 1 isoform X1 [Pan troglodytes] |
| GI:22538459 | RefSeq | XP_009440408.1 | 1440 | PREDICTED: nuclear receptor coactivator 1 isoform X2 [Pan troglodytes] |
| GI:22538457 | RefSeq | XP_009440409.1 | 1399 | PREDICTED: nuclear receptor coactivator 1 isoform X3 [Pan troglodytes] |
| GI:22538459 | SwissProt | Q15788.3 | 1441 | RecName: Full=Nuclear receptor coactivator 1; Short=NCoA-1; AltName: Full=Class E basic helix-loop-helix protein 74; Short=bHLHe74; AltName: Full=Protein Hin-2; AltName: Full=RIP160; AltName: Full=Renal carcinoma antigen NY-REN-52; AltName: Full=Steroid receptor coactivator 1; Short=SRC-1 [Homo sapiens] |