Gene/Proteome Database (LMPD)

LMPD ID
LMP006643
Gene ID
2712
Species
Homo sapiens (Human)
Gene Name
glycerol kinase 2
Gene Symbol
GK2
Synonyms
GKP2; GKTA
Alternate Names
glycerol kinase 2; glycerokinase 2; glycerol kinase pseudogene 2; glycerol kinase testis specific 2; glycerol kinase, testis specific 2; ATP:glycerol 3-phosphotransferase 2
Chromosome
4
Map Location
4q13
EC Number
2.7.1.30

Proteins

glycerol kinase 2
Refseq ID NP_149991
Protein GI 41393575
UniProt ID Q14410
mRNA ID NM_033214
Length 553
RefSeq Status VALIDATED
MAAPKTAAVGPLVGAVVQGTNSTRFLVFNSKTAELLSHHKVELTQEFPKEGWVEQDPKEILQSVYECIARTCEKLDELNIDISNIKAVGVSNQRETTVIWDKLTGEPLYNAVVWLDLRTQTTVEDLSKKIPGNSNFVKSKTGLPLSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKELCDFFEIPMDLLPNVFSSSEIYGLIKTGALEGVPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGREKPAYYALEGSVAIAGAVIRWLRDNLGIIETSGDIERLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRDCGIPLRHLQVDGGMTNNKVLMQLQADILHIPVIKPFMPETTALGAAMAAGAAEGVSVWSLEPQALSVLRMERFEPQIQATESEIRYATWKKAVMKSMGWVTSQSPEGGDPSIFSSLPLGFFIVSSMVMLIGARYISGVP

Gene Information

Entrez Gene ID
2712
Gene Name
glycerol kinase 2
Gene Symbol
GK2
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IDA:UniProt C extracellular vesicular exosome
GO:0005741 IEA:UniProtKB-KW C mitochondrial outer membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004370 NAS:UniProtKB F glycerol kinase activity
GO:0019563 IEA:UniProtKB-UniPathway P glycerol catabolic process
GO:0006072 IEA:InterPro P glycerol-3-phosphate metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
hsa00561 Glycerolipid metabolism
hsa03320 PPAR signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR018485 Carbohydrate kinase, FGGY, C-terminal
IPR018484 Carbohydrate kinase, FGGY, N-terminal
IPR018483 Carbohydrate kinase, FGGY, conserved site
IPR005999 Glycerol kinase

UniProt Annotations

Entry Information

Gene Name
glycerol kinase 2
Protein Entry
GLPK2_HUMAN
UniProt ID
Q14410
Species
Human

Comments

Comment Type Description
Catalytic Activity ATP + glycerol = ADP + sn-glycerol 3- phosphate.
Function Key enzyme in the regulation of glycerol uptake and metabolism.
Pathway Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
Similarity Belongs to the FGGY kinase family.
Subcellular Location Mitochondrion outer membrane ; Peripheral membrane protein ; Cytoplasmic side {ECO

Identical and Related Proteins

Unique RefSeq proteins for LMP006643 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
41393575 RefSeq NP_149991 553 glycerol kinase 2

Identical Sequences to LMP006643 proteins

Reference Database Accession Length Protein Name
GI:41393575 EMBL CBH19308.1 553 unnamed protein product [Homo sapiens]
GI:41393575 GenBank AAH48274.2 553 Glycerol kinase 2 [Homo sapiens]
GI:41393575 GenBank AHD79139.1 553 Sequence 28783 from patent US 8586006
GI:41393575 GenBank AIC54457.1 553 GK2, partial [synthetic construct]
GI:41393575 GenBank AIC62498.1 553 GK2, partial [synthetic construct]
GI:41393575 SwissProt Q14410.2 553 RecName: Full=Glycerol kinase 2; Short=GK 2; Short=Glycerokinase 2; AltName: Full=ATP:glycerol 3-phosphotransferase 2; AltName: Full=Glycerol kinase, testis specific 2 [Homo sapiens]

Related Sequences to LMP006643 proteins

Reference Database Accession Length Protein Name
GI:41393575 EMBL CAA55365.1 553 glycerol kinase [Homo sapiens]
GI:41393575 EMBL CBG09960.1 578 unnamed protein product [Pan troglodytes]
GI:41393575 EMBL CBV16791.1 578 unnamed protein product [Pan troglodytes]
GI:41393575 EMBL CBV23482.1 578 unnamed protein product [Pan troglodytes]
GI:41393575 GenBank AGX94636.1 578 Sequence 69541 from patent US 8541208
GI:41393575 GenBank AGY01503.1 578 Sequence 83220 from patent US 8541208