Gene/Proteome Database (LMPD)

LMPD ID
LMP006839
Gene ID
854888
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
D-arabinono-1,4-lactone oxidase
Gene Symbol
ALO1
Synonyms
-
Chromosome
XIII
EC Number
1.1.3.37

Proteins

D-arabinono-1,4-lactone oxidase
Refseq ID NP_013624
Protein GI 6323553
UniProt ID P54783
mRNA ID NM_001182445
Length 526
MSTIPFRKNYVFKNWAGIYSAKPERYFQPSSIDEVVELVKSARLAEKSLVTVGSGHSPSNMCVTDEWLVNLDRLDKVQKFVEYPELHYADVTVDAGMRLYQLNEFLGAKGYSIQNLGSISEQSVAGIISTGSHGSSPYHGLISSQYVNLTIVNGKGELKFLDAENDPEVFKAALLSVGKIGIIVSATIRVVPGFNIKSTQEVITFENLLKQWDTLWTSSEFIRVWWYPYTRKCVLWRGNKTTDAQNGPAKSWWGTKLGRFFYETLLWISTKIYAPLTPFVEKFVFNRQYGKLEKSSTGDVNVTDSISGFNMDCLFSQFVDEWGCPMDNGLEVLRSLDHSIAQAAINKEFYVHVPMEVRCSNTTLPSEPLDTSKRTNTSPGPVYGNVCRPFLDNTPSHCRFAPLENVTNSQLTLYINATIYRPFGCNTPIHKWFTLFENTMMVAGGKPHWAKNFLGSTTLAAGPVKKDTDYDDFEMRGMALKVEEWYGEDLKKFRKIRKEQDPDNVFLANKQWAIINGIIDPSELSD

Gene Information

Entrez Gene ID
854888
Gene Name
D-arabinono-1,4-lactone oxidase
Gene Symbol
ALO1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0031307 IDA:SGD C integral component of mitochondrial outer membrane
GO:0005739 IDA:SGD C mitochondrion
GO:0003885 IDA:SGD F D-arabinono-1,4-lactone oxidase activity
GO:0008762 IEA:InterPro F UDP-N-acetylmuramate dehydrogenase activity
GO:0050660 IEA:InterPro F flavin adenine dinucleotide binding
GO:0034599 IMP:SGD P cellular response to oxidative stress
GO:0070485 IMP:SGD P dehydro-D-arabinono-1,4-lactone biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY3O-6 dehydro-D-arabinono-1,4-lactone biosynthesis
PWY3O-6 dehydro-D-arabinono-1,4-lactone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR007173 ALO
IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
IPR006094 FAD linked oxidase, N-terminal
IPR016166 FAD-binding, type 2
IPR016167 FAD-binding, type 2, subdomain 1
IPR010031 FAD_lactone_oxidase
IPR023595 LGO_GLO
IPR006093 Oxy_OxRdtase_FAD_BS

UniProt Annotations

Entry Information

Gene Name
D-arabinono-1,4-lactone oxidase
Protein Entry
ALO_YEAST
UniProt ID
P54783
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity D-arabinono-1,4-lactone + O(2) = dehydro-D- arabinono-1,4-lactone + H(2)O(2).
Cofactor Name=FAD; Xref=ChEBI:CHEBI:57692;
Function Can oxidize L-gulono-1,4-lactone as well as D-arabinono- 1,4-lactone and L-galactono-1,4-lactone.
Interaction Self; NbExp=1; IntAct=EBI-2519, EBI-2519; P31787:ACB1; NbExp=1; IntAct=EBI-2519, EBI-2060; P38009:ADE17; NbExp=1; IntAct=EBI-2519, EBI-14223; P11076:ARF1; NbExp=1; IntAct=EBI-2519, EBI-2816; P53090:ARO8; NbExp=1; IntAct=EBI-2519, EBI-2042933; P43497:CWP2; NbExp=1; IntAct=EBI-2519, EBI-2044078; P32582:CYS4; NbExp=1; IntAct=EBI-2519, EBI-4167; Q12091:DAP1; NbExp=1; IntAct=EBI-2519, EBI-5554; P20449:DBP5; NbExp=1; IntAct=EBI-2519, EBI-5617; P54861:DNM1; NbExp=1; IntAct=EBI-2519, EBI-6002; P38295:EHT1; NbExp=1; IntAct=EBI-2519, EBI-20890; P39002:FAA3; NbExp=1; IntAct=EBI-2519, EBI-10089; P18411:FUN14; NbExp=1; IntAct=EBI-2519, EBI-20609; P32288:GLN1; NbExp=1; IntAct=EBI-2519, EBI-7665; P40582:GTT1; NbExp=1; IntAct=EBI-2519, EBI-7941; P22943:HSP12; NbExp=1; IntAct=EBI-2519, EBI-8548; Q6Q5K6:HUG1; NbExp=1; IntAct=EBI-2519, EBI-392766; P40581:HYR1; NbExp=1; IntAct=EBI-2519, EBI-7869; P47031:IML2; NbExp=1; IntAct=EBI-2519, EBI-25966; P11986:INO1; NbExp=1; IntAct=EBI-2519, EBI-9257; P00817:IPP1; NbExp=1; IntAct=EBI-2519, EBI-9338; P35844:KES1; NbExp=1; IntAct=EBI-2519, EBI-9648; Q12230:LSP1; NbExp=1; IntAct=EBI-2519, EBI-34978; P36060:MCR1; NbExp=1; IntAct=EBI-2519, EBI-10565; P28737:MSP1; NbExp=1; IntAct=EBI-2519, EBI-11435; Q03558:OYE2; NbExp=1; IntAct=EBI-2519, EBI-12729; P10963:PCK1; NbExp=1; IntAct=EBI-2519, EBI-13770; P37012:PGM2; NbExp=1; IntAct=EBI-2519, EBI-13296; P87284:PMP3; NbExp=1; IntAct=EBI-2519, EBI-13555; P22289:QCR9; NbExp=1; IntAct=EBI-2519, EBI-19947; P21524:RNR1; NbExp=1; IntAct=EBI-2519, EBI-15234; P09938:RNR2; NbExp=1; IntAct=EBI-2519, EBI-15240; P39954:SAH1; NbExp=1; IntAct=EBI-2519, EBI-16451; P14693:SAM35; NbExp=1; IntAct=EBI-2519, EBI-24602; P07560:SEC4; NbExp=1; IntAct=EBI-2519, EBI-16858; P25294:SIS1; NbExp=1; IntAct=EBI-2519, EBI-17244; P33328:SNC2; NbExp=1; IntAct=EBI-2519, EBI-17512; P39929:SNF7; NbExp=1; IntAct=EBI-2519, EBI-17554; Q00578:SSL2; NbExp=1; IntAct=EBI-2519, EBI-14683; P35180:TOM20; NbExp=1; IntAct=EBI-2519, EBI-12522; P07213:TOM70; NbExp=1; IntAct=EBI-2519, EBI-12551; P38342:TSC10; NbExp=1; IntAct=EBI-2519, EBI-21124; Q08926:UIP4; NbExp=1; IntAct=EBI-2519, EBI-2044051; P28274:URA7; NbExp=1; IntAct=EBI-2519, EBI-20128; P07806-1:VAS1 (xeno); NbExp=1; IntAct=EBI-2519, EBI-1009942; P0C268:YBL039W-B; NbExp=1; IntAct=EBI-2519, EBI-2044092; Q3E6R5:YDR381C-A; NbExp=1; IntAct=EBI-2519, EBI-2044020; P53206:YGR012W; NbExp=1; IntAct=EBI-2519, EBI-2044073; P38756:YHR003C; NbExp=1; IntAct=EBI-2519, EBI-24431; P38845:YHR146W; NbExp=1; IntAct=EBI-2519, EBI-24770; P01123:YPT1; NbExp=1; IntAct=EBI-2519, EBI-29496; P38555:YPT31; NbExp=1; IntAct=EBI-2519, EBI-29379; P51996:YPT32; NbExp=1; IntAct=EBI-2519, EBI-29384;
Miscellaneous Present with 6190 molecules/cell in log phase SD medium
Miscellaneous Present with 6190 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Pathway Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.
Ptm The N-terminus is blocked.
Similarity Belongs to the oxygen-dependent FAD-linked oxidoreductase family
Similarity Belongs to the oxygen-dependent FAD-linked oxidoreductase family. {ECO:0000305}.
Similarity Contains 1 FAD-binding PCMH-type domain
Similarity Contains 1 FAD-binding PCMH-type domain. {ECO:0000255|PROSITE-ProRule:PRU00718}.
Subcellular Location Mitochondrion membrane. Note=Membrane- embedded.

Identical and Related Proteins

Unique RefSeq proteins for LMP006839 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323553 RefSeq NP_013624 526 D-arabinono-1,4-lactone oxidase

Identical Sequences to LMP006839 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP006839 proteins

Reference Database Accession Length Protein Name