LIPID MAPS

LMPD ID

LMP006943

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Coq4p

Gene Symbol

COQ4

Synonyms

-

Chromosome

IV

Coq4p
Refseq ID	NP_010490
Protein GI	6320410
UniProt ID	O13525
mRNA ID	NM_001180512
Length	335
MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLADAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAISGWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMDKLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITNMPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSCKPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTPA

Entrez Gene ID

Gene Name

Coq4p

Gene Symbol

COQ4

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0031314	IEA:UniProtKB-HAMAP	C	extrinsic component of mitochondrial inner membrane
GO:0005743	IDA:UniProtKB	C	mitochondrial inner membrane
GO:0006744	IMP:UniProtKB	P	ubiquinone biosynthetic process

Accession	Description
IPR007715	Ubiquinone biosynthesis protein Coq4
IPR027540	Ubiquinone biosynthesis protein Coq4, eukaryotes

Gene Name

Coq4p

Protein Entry

COQ4_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of COQ3, COQ4, COQ6, COQ7 and COQ9 polypeptides. {ECO:0000255\|HAMAP-Rule:MF_03111, ECO:0000269\|PubMed:15548532, ECO:0000269\|PubMed:17391640, ECO:0000269\|PubMed:19022396}.
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255\|HAMAP-Rule:MF_03111}.
Similarity	Belongs to the COQ4 family. {ECO:0000255\|HAMAP- Rule:MF_03111}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000255\|HAMAP-Rule:MF_03111, ECO:0000269\|PubMed:11469793, ECO:0000269\|PubMed:14562095}; Peripheral membrane protein {ECO:0000255\|HAMAP-Rule:MF_03111, ECO:0000269\|PubMed:11469793, ECO:0000269\|PubMed:14562095}; Matrix side {ECO:0000255\|HAMAP- Rule:MF_03111, ECO:0000269\|PubMed:11469793, ECO:0000269\|PubMed:14562095}.
Subunit	Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with COQ3. {ECO:0000255\|HAMAP-Rule:MF_03111, ECO:0000269\|PubMed:15792955, ECO:0000269\|PubMed:16624818, ECO:0000269\|PubMed:17391640}.