LIPID MAPS

LMPD ID

LMP007303

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Fcp1p

Gene Symbol

FCP1

Synonyms

-

Chromosome

XIII

EC Number

3.1.3.16

Fcp1p
Refseq ID	NP_014004
Protein GI	6323933
UniProt ID	Q03254
mRNA ID	NM_001182784
Length	732
MTTQIRSPQGLPYPIQIDKLIPSVGSYLHEGDRLLVYKFWYLVERASDTGDDDNEHDVSPGGSAGSNGVSPPTKQLRESIEFFESPYEGDLISWNVDVGDEVATANQVICEIKRPCNHDIVYGGLCTQCGKEVSADAFDGVPLDVVGDVDLQISETEAIRTGKALKEHLRRDKKLILVVDLDQTIIHCGVDPTIAEWKNDPNNPNFETLRDVKSFTLDEELVLPLMYMNDDGSMLRPPPVRKCWYYVKVRPGLKEFFAKVAPLFEMHIYTMATRAYALQIAKIVDPTGELFGDRILSRDENGSLTTKSLAKLFPTDQSMVVVIDDRGDVWNWCPNLIKVVPYNFFVGVGDINSNFLPKQSTGMLQLGRKTRQKSQESQELLTDIMDNEKKLQEKIDKEVKRQEEKLNHQLATAEEPPANESKEELTKKLEYSASLEVQQQNRPLAKLQKHLHDQKLLVDDDDELYYLMGTLSNIHKTYYDMLSQQNEPEPNLMEIIPSLKQKVFQNCYFVFSGLIPLGTDIQRSDIVIWTSTFGATSTPDIDYLTTHLITKNPSTYKARLAKKFNPQIKIVHPDWIFECLVNWKKVDEKPYTLIVDSPISDEELQNFQTQLQKRQEYLEETQEQQHMLTSQENLNLFAAGTSWLNNDDDEDIPDTASDDDEDDDHDDESDDENNSEGIDRKRSIEDNHDDTSQKKTKAEPSQDGPVQHKGEGDDNEDSDSQLEEELMDMLDD

Entrez Gene ID

Gene Name

Fcp1p

Gene Symbol

FCP1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005829	IDA:SGD	C	cytosol
GO:0005634	IDA:SGD	C	nucleus
GO:0004722	IDA:SGD	F	protein serine/threonine phosphatase activity
GO:0070940	IDA:SGD	P	dephosphorylation of RNA polymerase II C-terminal domain
GO:0006357	IMP:SGD	P	regulation of transcription from RNA polymerase II promoter

REACTOME Pathway ID	Description
5618257	Formation of the Early Elongation Complex
5618068	Gene Expression
5618118	RNA Polymerase II Transcription
5618258	RNA Polymerase II Transcription Elongation

Gene Name

Fcp1p

Protein Entry

FCP1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Catalytic Activity	[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
Function	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II
Function	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II. {ECO:0000269\|PubMed:10445027}.
Miscellaneous	Present with 6550 molecules/cell in log phase SD medium
Miscellaneous	Present with 6550 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Contains 1 BRCT domain. {ECO:0000255\|PROSITE- ProRule:PRU00033}.
Similarity	Contains 1 FCP1 homology domain. {ECO:0000255\|PROSITE- ProRule:PRU00336}.
Subcellular Location	Nucleus.