Gene/Proteome Database (LMPD)

LMPD ID
LMP007441
Gene ID
853941
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase GPT2
Gene Symbol
GPT2
Synonyms
GAT1
Chromosome
XI
EC Number
2.3.1.15

Proteins

bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase GPT2
Refseq ID NP_012993
Protein GI 398365317
UniProt ID P36148
mRNA ID NM_001179857
Length 743
MSAPAADHNAAKPIPHVPQASRRYKNSYNGFVYNIHTWLYDVSVFLFNILFTIFFREIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAGKSRSRMPCFVTAESSFKKRFISFFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHPEIIKGRSKNPQTTPVNFTKRFSAKSLLGLPDYLSNAQIKEIPDDETIILSSPFRTSKSKVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHDRPSLLPIKAGVAIMALGAVAADPTMKVAVVPCGLHYFHRNKFRSRAVLEYGEPIVVDGKYGEMYKDSPRETVSKLLKKITNSLFSVTENAPDYDTLMVIQAARRLYQPVKVRLPLPAIVEINRRLLFGYSKFKDDPRIIHLKKLVYDYNRKLDSVGLKDHQVMQLKTTKLEALRCFVTLIVRLIKFSVFAILSLPGSILFTPIFIICRVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALILAPILYVTYSILLIILARKQHYCRIWVPSNNAFIQFVYFYALLVFTTYSSLKTGEIGVDLFKSLRPLFVSIVYPGKKIEEIQTTRKNLSLELTAVCNDLGPLVFPDYDKLATEIFSKRDGYDVSSDAESSISRMSVQSRSRSSSIHSIGSLASNALSRVNSRGSLTDIPIFSDAKQGQWKSEGETSEDEDEFDEKNPAIVQTARSSDLNKENSRNTNISSKIASLVRQKREHEKKE

Gene Information

Entrez Gene ID
853941
Gene Name
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase GPT2
Gene Symbol
GPT2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:SGD C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005811 IDA:SGD C lipid particle
GO:0004366 IDA:SGD F glycerol-3-phosphate O-acyltransferase activity
GO:0016287 IDA:SGD F glycerone-phosphate O-acyltransferase activity
GO:0016024 IEA:UniProtKB-UniPathway P CDP-diacylglycerol biosynthetic process
GO:0008654 IDA:SGD P phospholipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00561 Glycerolipid metabolism
sce00561 Glycerolipid metabolism
ko00564 Glycerophospholipid metabolism
sce00564 Glycerophospholipid metabolism
sce01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5667 CDP-diacylglycerol biosynthesis
PWY3O-6407 phosphatidate biosynthesis I (the dihydroxyacetone pathway)
PWY3O-6499 phosphatidate biosynthesis II (the glycerol-3-phosphate pathway)
PWY4FS-8 phosphatidylglycerol biosynthesis
PWY-7411 superpathway phosphatidate biosynthesis (yeast)
PWY-7411 superpathway phosphatidate biosynthesis (yeast)
TRIGLSYN-PWY triacylglycerol biosynthesis
TRIGLSYN-PWY triacylglycerol biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase GPT2
Protein Entry
GPT2_YEAST
UniProt ID
P36148
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate.
Catalytic Activity Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1- acyl-sn-glycerol 3-phosphate.
Function G-3-P/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase
Function G-3-P/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase. {ECO:0000269|PubMed:11544256}.
Miscellaneous Present with 3100 molecules/cell in log phase SD medium
Miscellaneous Present with 3100 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Pathway Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
Similarity Belongs to the GPAT/DAPAT family
Similarity Belongs to the GPAT/DAPAT family. {ECO:0000305}.
Subcellular Location Membrane ; Multi-pass membrane protein .
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007441 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398365317 RefSeq NP_012993 743 bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase GPT2

Identical Sequences to LMP007441 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007441 proteins

Reference Database Accession Length Protein Name