Gene/Proteome Database (LMPD)

LMPD ID
LMP007540
Gene ID
946569
Species
Escherichia coli K-12 (E. coli)
Gene Name
colanic acid biosynthesis protein
Gene Symbol
wcaK
Synonyms
ECK2039; JW2030
Summary
Overexpression causes a decrease in the amount of biofilm formed. [More information is available at EcoGene: EG13577]. WcaK may be involved in colanic acid synthesis based on sequence and its presence in a putative colanic acid synthesis operon , though there is no evidence suggesting a function for this protein. [More information is available at EcoCyc: G7096].
Orthologs
View orthologs and multiple alignments for wcaK

Proteins

colanic acid biosynthesis protein [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_416549
Protein GI 16129985
UniProt ID P71242
Length 426
RefSeq Status REVIEWED
MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPVSSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNIAIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGPFQDEQFNQLANYVFGHCDALILRESVSFDLMKRSNITTAKVEHGVDTAWLVDHHTEDFTASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQVIALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGTRLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQLPALNARLSEAVSRERQTGMQMVQSVLERIGEVK

Gene Information

Entrez Gene ID
946569
Gene Name
colanic acid biosynthesis protein
Gene Symbol
wcaK
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016740 IEA:UniProtKB-KW F transferase activity
GO:0009103 IEA:UniProtKB-KW P lipopolysaccharide biosynthetic process
GO:0045228 IEA:UniProtKB-UniPathway P slime layer polysaccharide biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
COLANSYN-PWY colanic acid building blocks biosynthesis
PWY-6317 galactose degradation I (Leloir pathway)

Domain Information

InterPro Annotations

Accession Description
IPR023918 Colanic_acid_synth_WcaK
IPR007345 Polysacch_pyruvyl_Trfase

UniProt Annotations

Entry Information

Gene Name
colanic acid biosynthesis protein
Protein Entry
WCAK_ECOLI
UniProt ID
P71242
Species
E. coli

Comments

Comment Type Description
Pathway Slime biogenesis; slime polysaccharide biosynthesis.
Similarity Belongs to the polysaccharide pyruvyl transferase family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007540 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16129985 RefSeq NP_416549 426 colanic acid biosynthesis protein [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007540 proteins

Reference Database Accession Length Protein Name
GI:16129985 EMBL CDY59351.1 426 predicted colanic acid biosynthesis pyruvyl transferase [Escherichia coli]
GI:16129985 EMBL CDZ20866.1 426 predicted colanic acid biosynthesis pyruvyl transferase [Escherichia coli]
GI:16129985 GenBank KGA85589.1 426 colanic acid biosynthesis protein [Escherichia coli]
GI:16129985 GenBank KGL68987.1 426 colanic acid biosynthesis protein [Escherichia coli NCTC 50110]
GI:16129985 gnl PRJNA257976 426 colanic acid biosynthesis protein [Escherichia coli BW25113]
GI:16129985 gnl IGS 426 colanic acid biosynthesis protein [Escherichia coli ER2796]

Related Sequences to LMP007540 proteins

Reference Database Accession Length Protein Name
GI:16129985 GenBank EGJ02239.1 426 amylovoran biosynthesis protein amsJ [Shigella boydii 3594-74]
GI:16129985 GenBank EOV12673.1 426 colanic acid biosynthesis protein wcaK [Escherichia coli KTE40]
GI:16129985 GenBank EOV39238.1 426 colanic acid biosynthesis protein wcaK [Escherichia coli KTE221]
GI:16129985 GenBank KDU64616.1 426 colanic acid biosynthesis pyruvyl transferase WcaK [Escherichia coli 4-203-08_S1_C1]
GI:16129985 GenBank KDX45092.1 426 colanic acid biosynthesis pyruvyl transferase WcaK [Escherichia coli 2-177-06_S3_C2]
GI:16129985 RefSeq YP_407370.1 426 pyruvyl transferase [Shigella boydii Sb227]