Gene/Proteome Database (LMPD)

LMPD ID
LMP008074
Gene ID
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein F26E4.12
Gene Symbol
Synonyms
CELE_F26E4.12
Chromosome
I
EC Number
1.11.1.9;

Proteins

Protein F26E4.12
Refseq ID NP_492598
Protein GI 17506887
UniProt ID O02621
mRNA ID NM_060197
Length 163
MSSVYDFNVKNANGDDVSLSDYKGKVLIIVNVASQCGLTNKNYTQLKELLDVYKKDGLEVLAFPCNQFAGQEPSCEIDIQAFVADKFKFEPTLFQKIDVNGDKQSPLFKFLKNEKGGFMFDAIKWNFTKFLVGRDGKIIKRFGPTTDPKDMEKDIKEALGEKL

Gene Information

Entrez Gene ID
Gene Name
Protein F26E4.12
Gene Symbol
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0004602 IEA:UniProtKB-EC F glutathione peroxidase activity
GO:0047066 IMP:WormBase F phospholipid-hydroperoxide glutathione peroxidase activity
GO:0045087 IEP:WormBase P innate immune response
GO:0055114 IMP:WormBase P oxidation-reduction process
GO:0090087 IMP:WormBase P regulation of peptide transport
GO:0006979 IEA:InterPro P response to oxidative stress

KEGG Pathway Links

KEGG Pathway ID Description
cel00590 Arachidonic acid metabolism
ko00590 Arachidonic acid metabolism
cel00480 Glutathione metabolism
ko00480 Glutathione metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
5652697 Arachidonic acid metabolism
5652491 Metabolism
5652530 Metabolism of lipids and lipoproteins
5653473 Synthesis of 12-eicosatetraenoic acid derivatives
5653472 Synthesis of 5-eicosatetraenoic acids

Domain Information

InterPro Annotations

Accession Description
IPR000889 Glutathione peroxidase
IPR029759 Glutathione peroxidase active site
IPR029760 Glutathione peroxidase conserved site
IPR012336 Thioredoxin-like fold

UniProt Annotations

Entry Information

Gene Name
Protein F26E4.12
Protein Entry
GPX1_CAEEL
UniProt ID
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity 2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
Function May constitute a glutathione peroxidase-like protective system against oxidative stresses
Function May constitute a glutathione peroxidase-like protective system against oxidative stresses. {ECO:0000250}.
Similarity Belongs to the glutathione peroxidase family
Similarity Belongs to the glutathione peroxidase family. {ECO:0000305}.
Subcellular Location Cytoplasm .
Subcellular Location Cytoplasm {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008074 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17506887 RefSeq NP_492598 163 Protein F26E4.12

Identical Sequences to LMP008074 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP008074 proteins

Reference Database Accession Length Protein Name