Gene/Proteome Database (LMPD)

LMPD ID
LMP010634
Gene ID
815657
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
Monogalactosyldiacylglycerol synthase 3
Gene Symbol
MGDC
Synonyms
ATMGD3; F7E22.4; F7E22_4; MGD3; MGDC; MONOGALACTOSYL DIACYLGLYCEROL SYNTHASE 3; MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE; monogalactosyldiacylglycerol synthase type C
Alternate Names
Monogalactosyldiacylglycerol synthase 3
Chromosome
2
EC Number
2.4.1.46
Summary
MGD3 is the major enzyme for galactolipid metabolism during phosphate starvation. Does not contribute to galactolipid synthesis under P1-sufficient conditions.
Orthologs
View orthologs and multiple alignments for MGDC

Proteins

Monogalactosyldiacylglycerol synthase 3
Refseq ID NP_565352
Protein GI 18397057
UniProt ID Q9SI93
mRNA ID NM_126865
Length 465
RefSeq Status REVIEWED
MMKVVSPRTRSDSITEKVFRRVYSNFNISTVEDEYIHRQRSSDYEKESRLRKRGLEDKEEVMEMEQMGAERIKTVLILMSDTGGGHRASAEAIRDAFKIEFGDDYRIIIKDVWKEYTGWPLNDMERQYKFMVKHVGLWSVAFHGTSPKWIHKSYLSALAAYYAKEIEAGLMEYKPDIIISVHPLMQHIPLWVMKWQGLHKKVIFVTVITDLNTCHRTWFHHGVSRCYCPSKEVAKRALVDGLDDSQIRVFGLPVRPSFPRTILNKNELRKELEIDLNLPAVLLMGGGEGMGPVQKTALALGDSLYNSKESNPIGQLIVICGRNKVLASTLASHEWKIPVKVRGFETQMEKWMGACDCIITKAGPGTIAEALICGLPIILNDYIPGQEKGNVPYVVDNGAGVFTRSPKETAKIVADWFSNNKEELKKMSENALKLSQPEAVFDIVKDIHHLSNRIPLFNEFSY
Monogalactosyldiacylglycerol synthase 3
Refseq ID NP_001118301
Protein GI 186500120
UniProt ID Q9SI93
mRNA ID NM_001124829
Length 362
RefSeq Status REVIEWED
MMKVVSPRTRSDSITEKVFRRVYSNFNISTVEDEYIHRQRSSDYEKESRLRKRGLEDKEEVMEMEQMGAERIKTVLILMSDTGGGHRASAEAIRDAFKIEFGDDYRIIIKDVWKEYTGWPLNDMERQYKFMVKHVGLWSVAFHGTSPKWIHKSYLSALAAYYAKEIEAGLMEYKPDIIISVHPLMQHIPLWVMKWQGLHKKVIFVTVITDLNTCHRTWFHHGVSRCYCPSKEVAKRALVDGLDDSQIRVFGLPVRPSFPRTILNKNELRKELEIDLNLPAVLLMGGGEGMGPVQKTALALGDSLYNSKESNPIGQLIVICGRNKVLASTLASHEWKIPVKVRGFETQMEKWMGACDCIITKH

Gene Information

Entrez Gene ID
815657
Gene Name
Monogalactosyldiacylglycerol synthase 3
Gene Symbol
MGDC
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IEA:UniProtKB-KW C chloroplast
GO:0009527 IEA:UniProtKB-KW C plastid outer membrane
GO:0046509 IEA:UniProtKB-EC F 1,2-diacylglycerol 3-beta-galactosyltransferase activity
GO:0030246 IEA:InterPro F carbohydrate binding
GO:0016036 IGI:TAIR P cellular response to phosphate starvation
GO:0006631 IMP:TAIR P fatty acid metabolic process
GO:0019374 IMP:TAIR P galactolipid metabolic process
GO:0009247 IEA:InterPro P glycolipid biosynthetic process
GO:0030259 IEA:InterPro P lipid glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
ath00561 Glycerolipid metabolism
ath01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-401 glycolipid biosynthesis
PWY-401 glycolipid biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR009695 Diacylglycerol glucosyltransferase, N-terminal
IPR007235 Glycosyl transferase, family 28, C-terminal

UniProt Annotations

Entry Information

Gene Name
Monogalactosyldiacylglycerol synthase 3
Protein Entry
MGDG3_ARATH
UniProt ID
Q9SI93
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9SI93-1; Sequence=Displayed; Name=2; IsoId=Q9SI93-2; Sequence=VSP_035389, VSP_035390; Note=Derived from EST data. No experimental confirmation available.;
Biophysicochemical Properties pH dependence: Optimum pH is 7.0.;
Catalytic Activity UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol = UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol.
Developmental Stage Mostly expressed in early stages of development. {ECO:0000269|PubMed:11553816}.
Function Involved in the synthesis of the major structural component of photosynthetic membranes and in the chloroplast envelope biogenesis. Can use both prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2-diacylglycerol species, but operates with some preference for the eukaryotic one. {ECO:0000269|PubMed:11553816}.
Induction Induced by phosphate deprivation. {ECO:0000269|PubMed:11553816, ECO:0000269|PubMed:14730084, ECO:0000269|PubMed:16762032}.
Miscellaneous Auxin activates expression during Pi starvation, whereas cytokinin represses it.
Similarity Belongs to the glycosyltransferase 28 family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast outer membrane {ECO:0000305|PubMed:11553816}.
Tissue Specificity Expressed mainly in roots. Detected in flowers, leaves, stems, siliques and pollen tubes. {ECO:0000269|PubMed:11553816, ECO:0000269|PubMed:14730084}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010634 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18397057 RefSeq NP_565352 465 Monogalactosyldiacylglycerol synthase 3
186500120 RefSeq NP_001118301 362 Monogalactosyldiacylglycerol synthase 3

Identical Sequences to LMP010634 proteins

Reference Database Accession Length Protein Name
GI:18397057 GenBank ABH04464.1 465 At2g11810 [Arabidopsis thaliana]
GI:18397057 GenBank ACW86311.1 465 Sequence 2593 from patent US 7569389
GI:18397057 GenBank AEC06183.1 465 Monogalactosyldiacylglycerol synthase 3 [Arabidopsis thaliana]
GI:186500120 GenBank AEC06184.1 362 Monogalactosyldiacylglycerol synthase 3 [Arabidopsis thaliana]
GI:18397057 GenBank AHL38857.1 465 glycosyltransferase, partial [Arabidopsis thaliana]
GI:18397057 gnl TIGR 465 putative monogalactosyldiacylglycerol synthase [Arabidopsis thaliana]
GI:18397057 SwissProt Q9SI93.2 465 RecName: Full=Monogalactosyldiacylglycerol synthase 3, chloroplastic; Short=AtMGD3; AltName: Full=MGDG synthase type C; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010634 proteins

Reference Database Accession Length Protein Name
GI:186500120 GenBank ABH04464.1 465 At2g11810 [Arabidopsis thaliana]
GI:18397057 GenBank ACW86310.1 472 Sequence 2592 from patent US 7569389
GI:18397057 GenBank ACW86312.1 464 Sequence 2594 from patent US 7569389
GI:18397057 GenBank EFH60031.1 466 hypothetical protein ARALYDRAFT_899522 [Arabidopsis lyrata subsp. lyrata]
GI:186500120 GenBank AEC06183.1 465 Monogalactosyldiacylglycerol synthase 3 [Arabidopsis thaliana]
GI:18397057 GenBank EOA30514.1 466 hypothetical protein CARUB_v10013637mg [Capsella rubella]
GI:186500120 GenBank AHL38857.1 465 glycosyltransferase, partial [Arabidopsis thaliana]
GI:186500120 gnl TIGR 465 putative monogalactosyldiacylglycerol synthase [Arabidopsis thaliana]
GI:186500120 RefSeq NP_565352.1 465 Monogalactosyldiacylglycerol synthase 3 [Arabidopsis thaliana]
GI:18397057 RefSeq XP_002883772.1 466 hypothetical protein ARALYDRAFT_899522 [Arabidopsis lyrata subsp. lyrata]
GI:18397057 RefSeq XP_006297616.1 466 hypothetical protein CARUB_v10013637mg [Capsella rubella]
GI:186500120 SwissProt Q9SI93.2 465 RecName: Full=Monogalactosyldiacylglycerol synthase 3, chloroplastic; Short=AtMGD3; AltName: Full=MGDG synthase type C; Flags: Precursor [Arabidopsis thaliana]