Gene/Proteome Database (LMPD)

LMPD ID
LMP010875
Gene ID
841961
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phospholipase D epsilon
Gene Symbol
PLDEPSILON
Synonyms
F7A10.25; F7A10_25; phospholipase D alpha 4; PLDALPHA4; PLDEPSILON
Alternate Names
phospholipase D epsilon
Chromosome
1
EC Number
3.1.4.4
Summary
member of C2-PLD. subfamily Represents a phospholipase D (PLD) gene with four exons, hence it is a member of the alpha class. Its amino acid sequence is quite different from other PLDs, therefore it might possess unique structural and/or catalytic properties.
Orthologs
View orthologs and multiple alignments for PLDEPSILON

Proteins

phospholipase D epsilon
Refseq ID NP_175914
Protein GI 15222670
UniProt ID Q9C888
mRNA ID NM_104391
Length 762
RefSeq Status REVIEWED
MELEEQKKYFHGTLEITIFDATPFSPPFPFNCICTKPKAAYVTIKINKKKVAKTSSEYDRIWNQTFQILCAHPVTDTTITITLKTRCSVLGRFRISAEQILTSNSAVINGFFPLIADNGSTKRNLKLKCLMWFRPAYLEPGWCRALEEASFQGIRNASFPQRSNCRVVLYQDAHHKATFDPRVDDVPFNARNLWEDVYKAIESARHLVYIAGWALNPNLVLVRDNETEIPHAVGVTVGELLKRKSEEGVAVRVMLWNDETSLPMIKNKGVMRTNVERALAYFRNTNVVCRLCPRLHKKLPTAFAHHQKTITLDTRVTNSSTKEREIMSFLGGFDLCDGRYDTEEHSLFRTLGTEADFYQTSVAGAKLSRGGPREPWHDCHVSVVGGAAWDVLKNFEQRWTKQCNPSVLVNTSGIRNLVNLTGPTEENNRKWNVQVLRSIDHISATEMPRGLPVEKSVHDGYVAAIRKAERFIYIENQYFMGSCDHWESKNDKICSGCTNLIPVEIALKIAAKIRARERFAVYIVIPMWPEGPPESETVEEILHWTRETMSMMYQIIGEAIWEVGDKSHPRDYLNFFCLANREEKRDGEFEAVSSPHQKTHYWNAQRNRRFMVYVHSKLMIVDDTYILIGSANINQRSMDGCRDTEIAIGCYQTNTNNTNEIQAYRLSLWYEHTGGKITADDLSSSEPESLECVRGLRTIGEQMWEIYSGDKVVDMLGIHLVAYPISVTGDGAVEEVGDGCFPDTKTLVKGKRSKMFPPVLTT

Gene Information

Entrez Gene ID
841961
Gene Name
phospholipase D epsilon
Gene Symbol
PLDEPSILON
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0005886 IDA:TAIR C plasma membrane
GO:0070290 IEA:UniProtKB-EC F N-acylphosphatidylethanolamine-specific phospholipase D activity
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004630 IDA:TAIR F phospholipase D activity
GO:0051301 IMP:TAIR P cell division
GO:0016049 IMP:TAIR P cell growth
GO:0006995 IMP:TAIR P cellular response to nitrogen starvation
GO:0016036 IMP:TAIR P cellular response to phosphate starvation
GO:0051365 IMP:TAIR P cellular response to potassium ion starvation
GO:0046470 IEA:InterPro P phosphatidylcholine metabolic process
GO:0009395 IDA:TAIR P phospholipid catabolic process
GO:0045848 IMP:TAIR P positive regulation of nitrogen utilization
GO:0009791 IMP:TAIR P post-embryonic development
GO:0006970 IMP:TAIR P response to osmotic stress
GO:0048364 IMP:TAIR P root development

KEGG Pathway Links

KEGG Pathway ID Description
ath04144 Endocytosis
ath00565 Ether lipid metabolism
ath00564 Glycerophospholipid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
6254320 Synthesis of PG

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR015679 Phospholipase D family
IPR024632 Phospholipase D, C-terminal
IPR011402 Phospholipase D, plant
IPR025202 Phospholipase D-like domain
IPR001736 Phospholipase D/Transphosphatidylase

UniProt Annotations

Entry Information

Gene Name
phospholipase D epsilon
Protein Entry
PLDE1_ARATH
UniProt ID
Q9C888
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity A phosphatidylcholine + H(2)O = choline + a phosphatidate.
Cofactor Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250};
Domain C2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes.
Function Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.
Similarity Belongs to the phospholipase D family. C2-PLD subfamily. {ECO:0000305}.
Similarity Contains 1 C2 domain. {ECO:0000305}.
Similarity Contains 2 PLD phosphodiesterase domains. {ECO:0000255|PROSITE-ProRule:PRU00153}.
Subcellular Location Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010875 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15222670 RefSeq NP_175914 762 phospholipase D epsilon

Identical Sequences to LMP010875 proteins

Reference Database Accession Length Protein Name
GI:15222670 GenBank AAG51567.1 762 phospholipase D alpha, putative; 90792-93364 [Arabidopsis thaliana]
GI:15222670 GenBank AEE33199.1 762 phospholipase D epsilon [Arabidopsis thaliana]
GI:15222670 SwissProt Q9C888.1 762 RecName: Full=Phospholipase D epsilon; Short=AtPLDepsilon; Short=PLD epsilon; AltName: Full=PLDalpha3 [Arabidopsis thaliana]

Related Sequences to LMP010875 proteins

Reference Database Accession Length Protein Name
GI:15222670 GenBank EFH70751.1 762 predicted protein [Arabidopsis lyrata subsp. lyrata]
GI:15222670 GenBank EOA37287.1 759 hypothetical protein CARUB_v10010904mg [Capsella rubella]
GI:15222670 RefSeq XP_002894492.1 762 predicted protein [Arabidopsis lyrata subsp. lyrata]
GI:15222670 RefSeq XP_006304389.1 759 hypothetical protein CARUB_v10010904mg [Capsella rubella]
GI:15222670 RefSeq XP_010462361.1 759 PREDICTED: phospholipase D epsilon-like [Camelina sativa]
GI:15222670 RefSeq XP_010480035.1 759 PREDICTED: phospholipase D epsilon [Camelina sativa]