Gene/Proteome Database (LMPD)
LMPD ID
LMP011541
Gene ID
Species
Danio rerio (Zebrafish)
Gene Name
choline phosphotransferase 1
Gene Symbol
Synonyms
sycp3; fd50f07; wu:fb67a04; wu:fd50f07
Alternate Names
cholinephosphotransferase 1; synaptonemal complex protein 3; diacylglycerol cholinephosphotransferase 1
Chromosome
4
EC Number
2.7.8.2
Proteins
| cholinephosphotransferase 1 | |
|---|---|
| Refseq ID | NP_997789 |
| Protein GI | 47086789 |
| UniProt ID | Q7ZW02 |
| mRNA ID | NM_212624 |
| Length | 382 |
| RefSeq Status | PROVISIONAL |
| MPQCECPEPLSAVQLKRLEEHKYSAAGRSLFEPPCQIYWNWLVQQIPTWVAPNTLTTIGLVINVITTVILVYYSPTATEEVPGWAFFLSALGLFIYQSLDAIDGKQARRTNSSSALGELFDHGCDAVSTVFVAVGTCICCGIGAYPNWMFFCGFVGMFMFFCAHWQTYVSGTLRFGLVDVTEVQIAIIIMYLLTAFTGVSFWEMRVPVLGVNLQTFPILGIIGGFLYSTYNYFFVIMNGGVGKNGSTVADTSVLTPGLHIGLILTLAFIIFKKSSSHLFEHHPCLYVLTFGMVIAKISNKLVVAHMTKSELHLQDTAFIGPGLLFLNQYFNSYIDEHIVLWIAMVLSLVDLVRYCTAVCLQIASHLRIRVFSISPQGHAHKD | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005794 | IEA:UniProtKB-KW | C | Golgi apparatus |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0004142 | IEA:UniProtKB-EC | F | diacylglycerol cholinephosphotransferase activity |
| GO:0046872 | IEA:UniProtKB-KW | F | metal ion binding |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| dre00565 | Ether lipid metabolism |
| dre00564 | Glycerophospholipid metabolism |
| dre_M00090 | Phosphatidylcholine (PC) biosynthesis, choline => PC |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 6176425 | Synthesis of PC |
Domain Information
UniProt Annotations
Entry Information
Gene Name
choline phosphotransferase 1
Protein Entry
CHPT1_DANRE
UniProt ID
Species
Zebrafish
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | CDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine. |
| Cofactor | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; |
| Function | Catalyzes phosphatidylcholine biosynthesis from CDP- choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity). {ECO:0000250}. |
| Pathway | Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2. |
| Similarity | Belongs to the CDP-alcohol phosphatidyltransferase class-I family. {ECO:0000305}. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP011541 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 47086789 | RefSeq | NP_997789 | 382 | cholinephosphotransferase 1 |
Identical Sequences to LMP011541 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:47086789 | GenBank | AAH45345.1 | 382 | Choline phosphotransferase 1 [Danio rerio] |
| GI:47086789 | SwissProt | Q7ZW02.1 | 382 | RecName: Full=Cholinephosphotransferase 1; AltName: Full=Diacylglycerol cholinephosphotransferase 1 [Danio rerio] |
Related Sequences to LMP011541 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:47086789 | RefSeq | XP_003452095.1 | 382 | PREDICTED: cholinephosphotransferase 1-like [Oreochromis niloticus] |
| GI:47086789 | RefSeq | XP_005811994.1 | 382 | PREDICTED: cholinephosphotransferase 1-like [Xiphophorus maculatus] |
| GI:47086789 | RefSeq | XP_007245035.1 | 382 | PREDICTED: cholinephosphotransferase 1 [Astyanax mexicanus] |
| GI:47086789 | RefSeq | XP_007579199.1 | 382 | PREDICTED: cholinephosphotransferase 1 [Poecilia formosa] |
| GI:47086789 | RefSeq | XP_008299215.1 | 382 | PREDICTED: cholinephosphotransferase 1 [Stegastes partitus] |
| GI:47086789 | RefSeq | XP_008398728.1 | 382 | PREDICTED: cholinephosphotransferase 1 [Poecilia reticulata] |