Gene/Proteome Database (LMPD)

LMPD ID
LMP011567
Gene ID
325922
Species
Danio rerio (Zebrafish)
Gene Name
retinol saturase (all-trans-retinol 13,14-reductase)
Gene Symbol
retsat
Synonyms
wu:fd46d06; zgc:113107
Alternate Names
putative all-trans-retinol 13,14-reductase; zRetSat A; all-trans-13,14-dihydroretinol saturase
Chromosome
3
EC Number
1.3.99.23

Proteins

putative all-trans-retinol 13,14-reductase precursor
Refseq ID NP_001015061
Protein GI 62632729
UniProt ID Q5BLE8
mRNA ID NM_001015061
Length 607
RefSeq Status PROVISIONAL
MWFAVVAIFLALVAFLYRYVVGSGPNPFAIDTREPLKPMVFDRKLKNKVLKQGFLASRVPEDLDAVVVGSGIGGLAIAVLLAKVGKKVLVLEQHDRAGGCCHTFKEQGFEFDVGIHYIGELSNHKPLRCIIDQMTNGQLQWDPLENPFDNVVIGPPENRRIYQIYSGRKRYMDELKKCFPGEEKAIDEYVRLCKEVGQGVWVMVLLKFLPTPIANFLVRTGLANRLTSFSRYASRSLTDVVNELTQNKDLRAVLSYIFGTYGKIPKEASFSMHSLIVNHYMNGAWYPKGGATEIAYHMIPIIEKAGGAVLVRAPVNRILLNDAKEAIGVSVLKGQEEVHVRAPIVISDAGIFNTYEYLLPKDVQTMPAIQKQLSMLQHGDSGLSIFIGLDGTKEELGLKADNYFIYPENNIDELLEDYRSGNREESAKKNPLIFVASPSAKDSTWPERTPGKSTLTVVSFANYEWFEEWKDDKVKNRSTDYKQLKELFINYILEAVTEIYPKIKDRIEYVDAGTPITNQHYIAAPRGEIYGADHGIPRFSAELNATIRAQTPIKNLYLTGQDLMLCGFAGALTGALTCGSVILNRNLHLEAFSLAKRVQNGNNKKKT

Gene Information

Entrez Gene ID
325922
Gene Name
retinol saturase (all-trans-retinol 13,14-reductase)
Gene Symbol
retsat
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IBA:RefGenome C endoplasmic reticulum membrane
GO:0051786 IDA:ZFIN F all-trans-retinol 13,14-reductase activity
GO:0042572 IBA:RefGenome P retinol metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
dre00830 Retinol metabolism
ko00830 Retinol metabolism

Domain Information

InterPro Annotations

Accession Description

UniProt Annotations

Entry Information

Gene Name
retinol saturase (all-trans-retinol 13,14-reductase)
Protein Entry
RETST_DANRE
UniProt ID
Q5BLE8
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity All-trans-13,14-dihydroretinol + acceptor = all-trans-retinol + reduced acceptor.
Cofactor Name=NAD(+); Xref=ChEBI:CHEBI:57540; Evidence={ECO:0000250}; Name=NADP(+); Xref=ChEBI:CHEBI:58349; Evidence={ECO:0000250}; Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
Function Retinol saturase carrying out the saturation of the 13- 14 double bond of all-trans-retinol to produce all-trans-13,14- dihydroretinol. {ECO:0000250}.
Similarity Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011567 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
62632729 RefSeq NP_001015061 607 putative all-trans-retinol 13,14-reductase precursor

Identical Sequences to LMP011567 proteins

Reference Database Accession Length Protein Name
GI:62632729 GenBank AAH90469.1 607 Retinol saturase (all-trans-retinol 13,14-reductase) [Danio rerio]
GI:62632729 SwissProt Q5BLE8.1 607 RecName: Full=Putative all-trans-retinol 13,14-reductase; AltName: Full=All-trans-13,14-dihydroretinol saturase; Short=RetSat; Flags: Precursor [Danio rerio]

Related Sequences to LMP011567 proteins

Reference Database Accession Length Protein Name
GI:62632729 GenBank AAI25972.1 607 Zgc:154169 [Danio rerio]
GI:62632729 RefSeq NP_001071261.1 607 all-trans-13,14-dihydroretinol saturase precursor [Danio rerio]
GI:62632729 RefSeq XP_003964953.1 610 PREDICTED: putative all-trans-retinol 13,14-reductase-like [Takifugu rubripes]
GI:62632729 RefSeq XP_003442053.2 630 PREDICTED: putative all-trans-retinol 13,14-reductase-like [Oreochromis niloticus]
GI:62632729 RefSeq XP_005726230.1 630 PREDICTED: putative all-trans-retinol 13,14-reductase-like [Pundamilia nyererei]
GI:62632729 RefSeq XP_008327686.1 610 PREDICTED: putative all-trans-retinol 13,14-reductase [Cynoglossus semilaevis]