Gene/Proteome Database (LMPD)

LMPD ID
LMP011694
Gene ID
Species
Danio rerio (Zebrafish)
Gene Name
phosphatidylserine synthase 1a
Gene Symbol
Synonyms
PSS-1; ptdss1; zgc:55906
Alternate Names
phosphatidylserine synthase 1; ptdSer synthase 1; serine-exchange enzyme I
Chromosome
16
EC Number
2.7.8.29

Proteins

phosphatidylserine synthase 1
Refseq ID NP_957250
Protein GI 41055684
UniProt ID Q803C9
mRNA ID NM_200956
Length 465
RefSeq Status PROVISIONAL
MATTFRSQTLSKDDVNYRMHFRMINEQQVEDITIQFFYKPHTISLLTVTVLSLMYFAFTRDDGDPDSNLRVGLILLVSFFLVISVLAFPNGPFTRPHPAIWRIVFGLSVLYFLFLVFIIFLNWDQVKALMFWLDPNLRYAKREADVMEYAVNCHVITWERILSHFDIFAFSHFWGWGMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMTVCRFLEMRTYHWASIKDIHSTTGKIKRAVLQFTPASWTYVRWLDPKSSLQRVMGVYLFMIIWQLTELNTFFLRHIFVFPACHALSWCRILFIGIITAPTVRQYYAYLTDTQCKRVGTQCWVFGAIAFLEALACIKFGQDLFSKTQILYVILWLVCLAFITFLCLYVMVWYAENYGPRQKSFSECEDSIYSEAGDSVTECKGEFEIDSTTSCSTRKRRDSGDSRTINGMEK

Gene Information

Entrez Gene ID
Gene Name
phosphatidylserine synthase 1a
Gene Symbol
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016740 IEA:UniProtKB-KW F transferase activity
GO:0006659 IEA:UniProtKB-UniPathway P phosphatidylserine biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
dre00564 Glycerophospholipid metabolism
dre01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
6175824 Glycerophospholipid biosynthesis
6176802 Synthesis of PS

Domain Information

InterPro Annotations

Accession Description
IPR004277 Phosphatidyl serine synthase

UniProt Annotations

Entry Information

Gene Name
phosphatidylserine synthase 1a
Protein Entry
PTSS1_DANRE
UniProt ID
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity L-1-phosphatidylethanolamine + L-serine = L-1- phosphatidylserine + ethanolamine.
Function Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine (By similarity). {ECO:0000250}.
Pathway Phospholipid metabolism; phosphatidylserine biosynthesis.
Similarity Belongs to the phosphatidyl serine synthase family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011694 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
41055684 RefSeq NP_957250 465 phosphatidylserine synthase 1

Identical Sequences to LMP011694 proteins

Reference Database Accession Length Protein Name
GI:41055684 GenBank AAH44533.1 465 Phosphatidylserine synthase 1 [Danio rerio]

Related Sequences to LMP011694 proteins

Reference Database Accession Length Protein Name
GI:41055684 RefSeq XP_004541513.1 468 PREDICTED: phosphatidylserine synthase 1-like [Maylandia zebra]
GI:41055684 RefSeq XP_005738551.1 468 PREDICTED: phosphatidylserine synthase 1-like [Pundamilia nyererei]
GI:41055684 RefSeq XP_005934847.1 468 PREDICTED: phosphatidylserine synthase 1-like isoform X1 [Haplochromis burtoni]
GI:41055684 RefSeq XP_005934848.1 468 PREDICTED: phosphatidylserine synthase 1-like isoform X2 [Haplochromis burtoni]
GI:41055684 RefSeq XP_008283918.1 468 PREDICTED: phosphatidylserine synthase 1 [Stegastes partitus]
GI:41055684 SwissProt Q803C9.2 465 RecName: Full=Phosphatidylserine synthase 1; Short=PSS-1; Short=PtdSer synthase 1; AltName: Full=Serine-exchange enzyme I [Danio rerio]