Gene/Proteome Database (LMPD)

LMPD ID
LMP012930
Gene ID
170926
Species
Rattus norvegicus (Rat)
Gene Name
cysteinyl leukotriene receptor 2
Gene Symbol
Cysltr2
Synonyms
Cyslt2;
Alternate Names
cysteinyl leukotriene receptor 2; RSBPT32; cysteinyl leukotriene CysLT2 receptor;
Chromosome
15
Map Location
15p11
Summary
putative cysteinyl leukotriene receptor [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Cysltr2

Proteins

cysteinyl leukotriene receptor 2
Refseq ID NP_596904
Protein GI 19173778
UniProt ID Q924T9
mRNA ID NM_133413
Length 309
MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL

Gene Information

Entrez Gene ID
170926
Gene Name
cysteinyl leukotriene receptor 2
Gene Symbol
Cysltr2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0001631 IEA:Ensembl F cysteinyl leukotriene receptor activity
GO:0070374 IMP:RGD P positive regulation of ERK1 and ERK2 cascade
GO:0045766 IMP:RGD P positive regulation of angiogenesis
GO:0010942 IMP:RGD P positive regulation of cell death

KEGG Pathway Links

KEGG Pathway ID Description
ko04020 Calcium signaling pathway
rno04020 Calcium signaling pathway
ko04080 Neuroactive ligand-receptor interaction
rno04080 Neuroactive ligand-receptor interaction

REACTOME Pathway Links

REACTOME Pathway ID Description
5954122 Class A/1 (Rhodopsin-like receptors)
5954202 Eicosanoid ligand-binding receptors
5953653 G alpha (q) signalling events
5953642 GPCR downstream signaling
5953758 GPCR ligand binding
5953537 Gastrin-CREB signalling pathway via PKC and MAPK
5954203 Leukotriene receptors
5953381 Signal Transduction
5953391 Signaling by GPCR

Domain Information

InterPro Annotations

Accession Description
IPR004071 Cysteinyl leukotriene receptor
IPR013311 Cysteinyl leukotriene receptor 2
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM

UniProt Annotations

Entry Information

Gene Name
cysteinyl leukotriene receptor 2
Protein Entry
CLTR2_RAT
UniProt ID
Q924T9
Species
Rat

Comments

Comment Type Description
Function Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (By similarity)
Similarity Belongs to the G-protein coupled receptor 1 family
Subcellular Location Cell membrane; Multi-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP012930 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
19173778 RefSeq NP_596904 309 cysteinyl leukotriene receptor 2

Identical Sequences to LMP012930 proteins

Reference Database Accession Length Protein Name
GI:19173778 GenBank ABT05399.1 309 Sequence 22 from patent US 7217800
GI:19173778 RefSeq XP_008769064.1 309 PREDICTED: cysteinyl leukotriene receptor 2 isoform X2 [Rattus norvegicus]
GI:19173778 RefSeq XP_008769065.1 309 PREDICTED: cysteinyl leukotriene receptor 2 isoform X2 [Rattus norvegicus]
GI:19173778 RefSeq XP_008769066.1 309 PREDICTED: cysteinyl leukotriene receptor 2 isoform X2 [Rattus norvegicus]

Related Sequences to LMP012930 proteins

Reference Database Accession Length Protein Name
GI:19173778 EMBL CAJ58196.1 309 unnamed protein product [Rattus norvegicus]
GI:19173778 RefSeq XP_008769064.1 309 PREDICTED: cysteinyl leukotriene receptor 2 isoform X2 [Rattus norvegicus]
GI:19173778 RefSeq XP_008769065.1 309 PREDICTED: cysteinyl leukotriene receptor 2 isoform X2 [Rattus norvegicus]
GI:19173778 SwissProt Q924T9.1 309 RecName: Full=Cysteinyl leukotriene receptor 2; Short=CysLTR2; AltName: Full=RSBPT32 [Rattus norvegicus]